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Plumbagin inhibits neuronal apoptosis, intimal hyperplasia and also suppresses TNF-α/NF-κB pathway induced inflammation and matrix metalloproteinase-2/9 expression in rat cerebral ischemia

Cerebral ischemic damage and infarction are well documented in stroke, which is presenting a foremost health concern globally with very high mortality and morbidity rates. Mechanisms that are associated with excitotoxicity, inflammation and oxidative stress are found to be critically involved in isc...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-Juan, Zhang, Jian-Guo, Wu, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116857/
https://www.ncbi.nlm.nih.gov/pubmed/30174499
http://dx.doi.org/10.1016/j.sjbs.2017.03.006