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PRDM9, a driver of the genetic map

During meiosis, maternal and paternal chromosomes undergo exchanges by homologous recombination. This is essential for fertility and contributes to genome evolution. In many eukaryotes, sites of meiotic recombination, also called hotspots, are regions of accessible chromatin, but in many vertebrates...

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Detalles Bibliográficos
Autores principales: Grey, Corinne, Baudat, Frédéric, de Massy, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116924/
https://www.ncbi.nlm.nih.gov/pubmed/30161134
http://dx.doi.org/10.1371/journal.pgen.1007479