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A database of simulated tumor genomes towards accurate detection of somatic small variants in cancer
Somatic mutations promote the transformation of normal cells to cancer. Accurate identification of such mutations facilitates cancer diagnosis and treatment, but biological and technological noises, including intra-tumor heterogeneity, sample contamination, uncertainties in base sequencing and read...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116990/ https://www.ncbi.nlm.nih.gov/pubmed/30161165 http://dx.doi.org/10.1371/journal.pone.0202982 |