Cargando…

NOP receptor pharmacological profile – A dynamic mass redistribution study

The Nociceptin/Orphanin FQ (N/OFQ) peptide NOP receptor is coupled to pertussis toxin (PTX)-sensitive G proteins (G(i/o)) whose activation leads to the inhibition of both cAMP production and calcium channel activity, and to the stimulation of potassium currents. The label free dynamic mass redistrib...

Descripción completa

Detalles Bibliográficos
Autores principales: Malfacini, Davide, Simon, Katharina, Trapella, Claudio, Guerrini, Remo, Zaveri, Nurulain T., Kostenis, Evi, Calo’, Girolamo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117024/
https://www.ncbi.nlm.nih.gov/pubmed/30161182
http://dx.doi.org/10.1371/journal.pone.0203021