Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3

OBJECTIVE: Peptidylarginine deiminase 2 (PAD2) and PAD4 are expressed in the synovium of rheumatoid arthritis (RA) patients and catalyze citrullination of arginine residues in proteins targeted by anti-citrullinated protein antibodies (ACPAs). Little is known about the relative importance of PAD2 an...

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Detalles Bibliográficos
Autores principales: Damgaard, Dres, Bawadekar, Mandar, Senolt, Ladislav, Stensballe, Allan, Shelef, Miriam A., Nielsen, Claus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117052/
https://www.ncbi.nlm.nih.gov/pubmed/30161253
http://dx.doi.org/10.1371/journal.pone.0203214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117052/
https://www.ncbi.nlm.nih.gov/pubmed/30161253
http://dx.doi.org/10.1371/journal.pone.0203214

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