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Application of dynamic modeling for survival estimation in advanced renal cell carcinoma

OBJECTIVE: In oncology, extrapolation of clinical outcomes beyond trial duration is traditionally achieved by parametric survival analysis using population-level outcomes. This approach may not fully capture the benefit/risk profile of immunotherapies due to their unique mechanisms of action. We eva...

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Detalles Bibliográficos
Autores principales: Deniz, Baris, Altincatal, Arman, Ambavane, Apoorva, Rao, Sumati, Doan, Justin, Malcolm, Bill, Michaelson, M. Dror, Yang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117067/
https://www.ncbi.nlm.nih.gov/pubmed/30161244
http://dx.doi.org/10.1371/journal.pone.0203406