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De novo assembly of a young Drosophila Y chromosome using single-molecule sequencing and chromatin conformation capture
While short-read sequencing technology has resulted in a sharp increase in the number of species with genome assemblies, these assemblies are typically highly fragmented. Repeats pose the largest challenge for reference genome assembly, and pericentromeric regions and the repeat-rich Y chromosome ar...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117089/ https://www.ncbi.nlm.nih.gov/pubmed/30059545 http://dx.doi.org/10.1371/journal.pbio.2006348 |