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The C. difficile clnRAB operon initiates adaptations to the host environment in response to LL-37

To cause disease, Clostridioides (Clostridium) difficile must resist killing by innate immune effectors in the intestine, including the host antimicrobial peptide, cathelicidin (LL-37). The mechanisms that enable C. difficile to adapt to the intestine in the presence of antimicrobial peptides are un...

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Detalles Bibliográficos
Autores principales: Woods, Emily C., Edwards, Adrianne N., Childress, Kevin O., Jones, Joshua B., McBride, Shonna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117091/
https://www.ncbi.nlm.nih.gov/pubmed/30125334
http://dx.doi.org/10.1371/journal.ppat.1007153