PIP(2) depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

We recently reported that the inward-rectifier Kir2.1 channel in brain capillary endothelial cells (cECs) plays a major role in neurovascular coupling (NVC) by mediating a neuronal activity-dependent, propagating vasodilatory (hyperpolarizing) signal. We further demonstrated that Kir2.1 activity is...

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Detalles Bibliográficos
Autores principales: Harraz, Osama F, Longden, Thomas A, Hill-Eubanks, David, Nelson, Mark T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117155/
https://www.ncbi.nlm.nih.gov/pubmed/30084828
http://dx.doi.org/10.7554/eLife.38689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117155/
https://www.ncbi.nlm.nih.gov/pubmed/30084828
http://dx.doi.org/10.7554/eLife.38689

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