Activation of the Calcium-Sensing Receptor Corrects the Impaired Mitochondrial Energy Status Observed in Renal Polycystin-1 Knockdown Cells Modeling Autosomal Dominant Polycystic Kidney Disease

Autosomal Dominant Polycistic kidney Disease (ADPKD) is a renal channelopathy due to loss-of-function mutations in the PKD1 or PKD2 genes, encoding polycystin-1 (PC1) or polycystin-2 (PC2), respectively. PC1 is a large protein found predominantly on the plasma membrane where interacts with different...

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Detalles Bibliográficos
Autores principales: Di Mise, Annarita, Ranieri, Marianna, Centrone, Mariangela, Venneri, Maria, Tamma, Grazia, Valenti, Daniela, Valenti, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117232/
https://www.ncbi.nlm.nih.gov/pubmed/30197885
http://dx.doi.org/10.3389/fmolb.2018.00077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117232/
https://www.ncbi.nlm.nih.gov/pubmed/30197885
http://dx.doi.org/10.3389/fmolb.2018.00077

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