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Clampdown of inflammation in aging and anticancer therapies by limiting upregulation and activation of GPCR, CXCR4
One of the major pathological outcomes of DNA damage during aging or anticancer therapy is enhanced inflammation. However, the underlying signaling mechanism that drives this is not well understood. Here, we show that in response to DNA damage, ubiquitously expressed GPCR, CXCR4 is upregulated throu...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117261/ https://www.ncbi.nlm.nih.gov/pubmed/30181898 http://dx.doi.org/10.1038/s41514-018-0028-0 |