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Luciferase-induced photoreductive uncaging of small-molecule effectors

Bioluminescence resonance energy transfer (BRET) is extensively used to study dynamic systems and has been utilized in sensors for studying protein proximity, metabolites, and drug concentrations. Herein, we demonstrate that BRET can activate a ruthenium-based photocatalyst which performs bioorthogo...

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Detalles Bibliográficos
Autores principales: Lindberg, Eric, Angerani, Simona, Anzola, Marcello, Winssinger, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117273/
https://www.ncbi.nlm.nih.gov/pubmed/30166547
http://dx.doi.org/10.1038/s41467-018-05916-9