RNA-binding protein LIN28B inhibits apoptosis through regulation of the AKT2/FOXO3A/BIM axis in ovarian cancer cells

LIN28B is an evolutionarily conserved RNA-binding protein that regulates mRNA translation and miRNA let-7 maturation in embryonic stem cells and developing tissues. Increasing evidence demonstrates that LIN28B is activated in cancer and serves as a critical oncogene. However, the underlying molecula...

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Detalles Bibliográficos
Autores principales: Lin, Xiaojuan, Shen, Jianfeng, Dan Peng, He, Xinhong, Xu, Congjian, Chen, Xiaojun, Tanyi, Janos L., Montone, Kathleen, Fan, Yi, Huang, Qihong, Zhang, Lin, Zhong, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117292/
https://www.ncbi.nlm.nih.gov/pubmed/30174831
http://dx.doi.org/10.1038/s41392-018-0026-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117292/
https://www.ncbi.nlm.nih.gov/pubmed/30174831
http://dx.doi.org/10.1038/s41392-018-0026-5

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