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Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination
Bacillus Calmette–Guérin (BCG) is the only licensed vaccine for tuberculosis (TB) and induces highly variable protection against pulmonary disease in different countries. We hypothesised that DNA methylation is one of the molecular mechanisms driving variability in BCG-induced immune responses. DNA...
Autores principales: | Hasso-Agopsowicz, Mateusz, Scriba, Thomas J., Hanekom, Willem A., Dockrell, Hazel M., Smith, Steven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117309/ https://www.ncbi.nlm.nih.gov/pubmed/30166570 http://dx.doi.org/10.1038/s41598-018-31537-9 |
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