NF1 deficiency correlates with estrogen receptor signaling and diminished survival in breast cancer

The key negative regulatory gene of the RAS pathway, NF1, is mutated or deleted in numerous cancer types and is associated with increased cancer risk and drug resistance. Even though women with neurofibromatosis (germline NF1 mutations) have a substantially increased breast cancer risk at a young ag...

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Detalles Bibliográficos
Autores principales: Dischinger, Patrick S., Tovar, Elizabeth A., Essenburg, Curt J., Madaj, Zachary B., Gardner, Eve E., Callaghan, Megan E., Turner, Ashley N., Challa, Anil K., Kempston, Tristan, Eagleson, Bryn, Kesterson, Robert A., Bronson, Roderick T., Bowman, Megan J., Graveel, Carrie R., Steensma, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117327/
https://www.ncbi.nlm.nih.gov/pubmed/30182054
http://dx.doi.org/10.1038/s41523-018-0080-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117327/
https://www.ncbi.nlm.nih.gov/pubmed/30182054
http://dx.doi.org/10.1038/s41523-018-0080-8

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