Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors

Granular cell tumors (GCTs) are rare tumors that can arise in multiple anatomical locations, and are characterized by abundant intracytoplasmic granules. The genetic drivers of GCTs are currently unknown. Here, we apply whole-exome sequencing and targeted sequencing analysis to reveal mutually exclu...

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Detalles Bibliográficos
Autores principales: Pareja, Fresia, Brandes, Alissa H., Basili, Thais, Selenica, Pier, Geyer, Felipe C., Fan, Dan, Da Cruz Paula, Arnaud, Kumar, Rahul, Brown, David N., Gularte-Mérida, Rodrigo, Alemar, Barbara, Bi, Rui, Lim, Raymond S., de Bruijn, Ino, Fujisawa, Sho, Gardner, Rui, Feng, Elvin, Li, Anqi, da Silva, Edaise M., Lozada, John R., Blecua, Pedro, Cohen-Gould, Leona, Jungbluth, Achim A., Rakha, Emad A., Ellis, Ian O., Edelweiss, Maria I. A., Palazzo, Juan, Norton, Larry, Hollmann, Travis, Edelweiss, Marcia, Rubin, Brian P., Weigelt, Britta, Reis-Filho, Jorge S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117336/
https://www.ncbi.nlm.nih.gov/pubmed/30166553
http://dx.doi.org/10.1038/s41467-018-05886-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117336/
https://www.ncbi.nlm.nih.gov/pubmed/30166553
http://dx.doi.org/10.1038/s41467-018-05886-y

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