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Chemo-immunotherapy of colon cancer with focused ultrasound and Salmonella-laden temperature sensitive liposomes (thermobots)

Using attenuated Salmonella that efficiently homes in solid tumors, here we developed thermobots that actively transported membrane attached low-temperature sensitive liposome (LTSL) inside colon cancer cells for triggered doxorubicin release and simultaneous polarized macrophages to M1 phenotype wi...

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Detalles Bibliográficos
Autores principales: Ektate, Kalyani, Munteanu, Maria Cristina, Ashar, Harshini, Malayer, Jerry, Ranjan, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117346/
https://www.ncbi.nlm.nih.gov/pubmed/30166607
http://dx.doi.org/10.1038/s41598-018-30106-4