Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution

Reprogramming of the NRPS/PKS assembly line is an attractive method for the production of new bioactive molecules. However, it is usually hampered by the loss of intimate domain/module interactions required for the precise control of chain transfer and elongation reactions. In this study, we first e...

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Detalles Bibliográficos
Autores principales: Awakawa, Takayoshi, Fujioka, Takuma, Zhang, Lihan, Hoshino, Shotaro, Hu, Zhijuan, Hashimoto, Junko, Kozone, Ikuko, Ikeda, Haruo, Shin-Ya, Kazuo, Liu, Wen, Abe, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117356/
https://www.ncbi.nlm.nih.gov/pubmed/30166552
http://dx.doi.org/10.1038/s41467-018-05877-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117356/
https://www.ncbi.nlm.nih.gov/pubmed/30166552
http://dx.doi.org/10.1038/s41467-018-05877-z

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