A Novel Function for 15-Lipoxygenases in Cholesterol Homeostasis and CCL17 Production in Human Macrophages

Arachidonate 15-lipoxygenase (ALOX15) and arachidonate 15-lipoxygenase, type B (ALOX15B) catalyze the dioxygenation of polyunsaturated fatty acids and are upregulated in human alternatively activated macrophages (AAMs) induced by Th2 cytokine interleukin-4 (IL-4) and/or interleukin-13. Known primari...

Descripción completa

Detalles Bibliográficos
Autores principales: Snodgrass, Ryan G., Zezina, Ekaterina, Namgaladze, Dmitry, Gupta, Sahil, Angioni, Carlo, Geisslinger, Gerd, Lütjohann, Dieter, Brüne, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117383/
https://www.ncbi.nlm.nih.gov/pubmed/30197642
http://dx.doi.org/10.3389/fimmu.2018.01906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117383/
https://www.ncbi.nlm.nih.gov/pubmed/30197642
http://dx.doi.org/10.3389/fimmu.2018.01906

Ejemplares similares