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Nano-particle engineered atorvastatin delivery to support mesenchymal stem cell survival in infarcted myocardium
Atorvastatin (ATV) may support mesenchymal stem cells (MSC) survival in post-infarct myocardium (MI) as inflammatory reactions, oxidative stress and hypoxia condition get started in such tissues after damage. However, limited aqueous insolubility and rapid first-pass metabolism reduce the systemic a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117435/ https://www.ncbi.nlm.nih.gov/pubmed/30174496 http://dx.doi.org/10.1016/j.sjbs.2017.03.015 |