Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis

The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) regulates cellular function in various cell types. Although the role of mTORC1 in skeletogenesis has been investigated previously, here we show a critical role of mTORC1/4E-BPs/SOX9 axis in regulating skeletogenesis through its express...

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Detalles Bibliográficos
Autores principales: Iezaki, Takashi, Horie, Tetsuhiro, Fukasawa, Kazuya, Kitabatake, Makoto, Nakamura, Yuka, Park, Gyujin, Onishi, Yuki, Ozaki, Kakeru, Kanayama, Takashi, Hiraiwa, Manami, Kitaguchi, Yuka, Kaneda, Katsuyuki, Manabe, Takayuki, Ishigaki, Yasuhito, Ohno, Mutsuhito, Hinoi, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117477/
https://www.ncbi.nlm.nih.gov/pubmed/30008325
http://dx.doi.org/10.1016/j.stemcr.2018.05.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117477/
https://www.ncbi.nlm.nih.gov/pubmed/30008325
http://dx.doi.org/10.1016/j.stemcr.2018.05.020

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