Compensatory Expression of Nur77 and Nurr1 Regulates NF-κB–Dependent Inflammatory Signaling in Astrocytes

Inflammatory activation of glial cells promotes loss of dopaminergic neurons in Parkinson disease. The transcription factor nuclear factor κB (NF-κB) regulates the expression of multiple neuroinflammatory cytokines and chemokines in activated glial cells that are damaging to neurons. Thus, inhibitio...

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Detalles Bibliográficos
Autores principales: Popichak, Katriana A., Hammond, Sean L., Moreno, Julie A., Afzali, Maryam F., Backos, Donald S., Slayden, Richard D., Safe, Stephen, Tjalkens, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117504/
https://www.ncbi.nlm.nih.gov/pubmed/30111648
http://dx.doi.org/10.1124/mol.118.112631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117504/
https://www.ncbi.nlm.nih.gov/pubmed/30111648
http://dx.doi.org/10.1124/mol.118.112631

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