Thapsigargin Increases IL-2 Production in T Cells at Nanomolar Concentrations

Thapsigargin (TGN) is a potent and selective inhibitor of sarco-endoplasmic Ca(2+)-ATPase, leading to rapid elevation of cytoplasmic Ca(2+) concentration. Previous reports have shown that TGN increases the production of various cytokines from macrophages and dendritic cells. Here, we examine the eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Ki-Hyang, Kim, Sang-Hyun, Jung, Ho-Hyun, Moon, Jun-Hyeok, Jeong, Seong-Un, Yu, Kyeongae, Lee, Chong-Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117510/
https://www.ncbi.nlm.nih.gov/pubmed/30181914
http://dx.doi.org/10.4110/in.2018.18.e26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117510/
https://www.ncbi.nlm.nih.gov/pubmed/30181914
http://dx.doi.org/10.4110/in.2018.18.e26

Ejemplares similares