Transverse cardiac slicing and optical imaging for analysis of transmural gradients in membrane potential and Ca(2+) transients in murine heart

KEY POINTS: A robust cardiac slicing approach was developed for optical mapping of transmural gradients in transmembrane potential (V (m)) and intracellular Ca(2+) transient (CaT) of murine heart. Significant transmural gradients in V (m) and CaT were observed in the left ventricle. Frequency‐depend...

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Detalles Bibliográficos
Autores principales: Wen, Q., Gandhi, K., Capel, Rebecca A., Hao, G., O'Shea, C., Neagu, G., Pearcey, S., Pavlovic, D., Terrar, Derek A., Wu, J., Faggian, G., Camelliti, Patrizia, Lei, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cardiovascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117587/
https://www.ncbi.nlm.nih.gov/pubmed/29928770
http://dx.doi.org/10.1113/JP276239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117587/
https://www.ncbi.nlm.nih.gov/pubmed/29928770
http://dx.doi.org/10.1113/JP276239

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