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Pitavastatin attenuates AGEs-induced mitophagy via inhibition of ROS generation in the mitochondria of cardiomyocytes

This study aimed to investigate whether pitavastatin protected against injury induced by advanced glycation end products products (AGEs) in neonatal rat cardiomyocytes, and to examine the underlying mechanisms. Cardiomyocytes of neonatal rats were incubated for 48 hours with AGEs (100μg/mL), recepto...

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Detalles Bibliográficos
Autores principales: Zha, Zhimin, Wang, Junhong, Li, Shiling, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117602/
https://www.ncbi.nlm.nih.gov/pubmed/29089470
http://dx.doi.org/10.7555/JBR.31.20160116