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Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents

To prevent implant failure due to fibrosis is a major objective in glaucoma research. The present study investigated the antifibrotic effects of paclitaxel (PTX), caffeic acid phenethyl ester (CAPE), and pirfenidone (PFD) coated microstent test specimens in a rat model. Test specimens based on a bio...

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Detalles Bibliográficos
Autores principales: Stahnke, Thomas, Siewert, Stefan, Reske, Thomas, Schmidt, Wolfram, Schmitz, Klaus-Peter, Grabow, Niels, Guthoff, Rudolf F., Wree, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117617/
https://www.ncbi.nlm.nih.gov/pubmed/30061178
http://dx.doi.org/10.1042/BSR20180628