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Up-regulation of microRNA-340 promotes osteosarcoma cell apoptosis while suppressing proliferation, migration, and invasion by inactivating the CTNNB1-mediated Notch signaling pathway

Osteosarcoma (OS) is the most common histological form of primary bone cancer. It is most prevalent in teenagers and young adults. The present study aims at exploring the regulatory effect of microRNA-340 (miR-340) on OS cell proliferation, invasion, migration, and apoptosis via regulating the Notch...

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Detalles Bibliográficos
Autores principales: Pan, Bao-Long, Wu, Ling, Pan, Li, Yang, Yu-Xi, Li, Hu-Huan, Dai, Yan-Juan, He, Zi-Qian, Tan, Ling, Huang, You-Guang, Tong, Zong-Wu, Liao, Jun-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117618/
https://www.ncbi.nlm.nih.gov/pubmed/29769415
http://dx.doi.org/10.1042/BSR20171615