Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products

Many fungal quinazolinone metabolites, which contain the methyl-indole pyrazino [1,2-b]quinazoline-3,6-dione core, have been found to possess promising antitumor activity. The purpose of this work was to synthesize the enantiomeric pairs of two members of this quinazolinone family, to explore their...

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Detalles Bibliográficos
Autores principales: Long, Solida, Resende, Diana I. S. P., Kijjoa, Anake, Silva, Artur M. S., Pina, André, Fernández-Marcelo, Tamara, Vasconcelos, M. Helena, Sousa, Emília, Pinto, Madalena M. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117665/
https://www.ncbi.nlm.nih.gov/pubmed/30065225
http://dx.doi.org/10.3390/md16080261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117665/
https://www.ncbi.nlm.nih.gov/pubmed/30065225
http://dx.doi.org/10.3390/md16080261

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