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Antitumor Activity of Quinazolinone Alkaloids Inspired by Marine Natural Products
Many fungal quinazolinone metabolites, which contain the methyl-indole pyrazino [1,2-b]quinazoline-3,6-dione core, have been found to possess promising antitumor activity. The purpose of this work was to synthesize the enantiomeric pairs of two members of this quinazolinone family, to explore their...
Autores principales: | Long, Solida, Resende, Diana I. S. P., Kijjoa, Anake, Silva, Artur M. S., Pina, André, Fernández-Marcelo, Tamara, Vasconcelos, M. Helena, Sousa, Emília, Pinto, Madalena M. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117665/ https://www.ncbi.nlm.nih.gov/pubmed/30065225 http://dx.doi.org/10.3390/md16080261 |
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