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Characterization of the Jomthonic Acids Biosynthesis Pathway and Isolation of Novel Analogues in Streptomyces caniferus GUA-06-05-006A
Jomthonic acids (JAs) are a group of natural products (NPs) with adipogenic activity. Structurally, JAs are formed by a modified β-methylphenylalanine residue, whose biosynthesis involves a methyltransferase that in Streptomyces hygroscopicus has been identified as MppJ. Up to date, three JA members...
Autores principales: | García-Salcedo, Raúl, Álvarez-Álvarez, Rubén, Olano, Carlos, Cañedo, Librada, Braña, Alfredo F., Méndez, Carmen, de la Calle, Fernando, Salas, José A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117699/ https://www.ncbi.nlm.nih.gov/pubmed/30065171 http://dx.doi.org/10.3390/md16080259 |
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