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First reported case of afatinib‐associated toxic megacolon

We report the first case of toxic megacolon associated with afatinib use, which is a potentially fatal complication, with risks of colonic perforation. In this case, the condition improved on stopping afatnib. Clinicians need to be alert of this rare but fatal adverse effect and to avoid anti‐diarrh...

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Detalles Bibliográficos
Autores principales: Kwok, Wang Chun, Tam, Terence Chi Chun, Lam, David Chi Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117793/
https://www.ncbi.nlm.nih.gov/pubmed/30186606
http://dx.doi.org/10.1002/rcr2.360