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Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells

Pixantrone (PIX) is an anticancer drug approved for the treatment of multiple relapsed or refractory aggressive B-cell non-Hodgkin's lymphoma. It is an aza-anthracenedione synthesized to have the same anticancer activity as its predecessors, anthracyclines (e.g. doxorubicin) and anthracenedione...

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Detalles Bibliográficos
Autores principales: Reis-Mendes, Ana, Alves, Marisa, Carvalho, Félix, Remião, Fernando, Bastos, Maria Lourdes, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Slovak Toxicology Society SETOX 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117818/
https://www.ncbi.nlm.nih.gov/pubmed/30181708
http://dx.doi.org/10.2478/intox-2018-0002