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Genetic variation in folate metabolism is associated with the risk of conotruncal heart defects in a Chinese population

BACKGROUND: Conotruncal heart defects (CTDs) are a subgroup of congenital heart defects that are considered to be the most common type of birth defect worldwide. Genetic disturbances in folate metabolism may increase the risk of CTDs. METHODS: We evaluated five single-nucleotide polymorphisms (SNPs)...

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Detalles Bibliográficos
Autores principales: Wang, Xike, Wei, Haitao, Tian, Ying, Wu, Yue, Luo, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117882/
https://www.ncbi.nlm.nih.gov/pubmed/30165839
http://dx.doi.org/10.1186/s12887-018-1266-9