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Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells

BACKGROUND: Currently, no FDA-approved vaccines or treatments are available for Ebola virus disease (EVD), and therapy remains largely supportive. Ebola virus (EBOV) has broad tissue tropism and can infect a variety of cells including epithelial cells. Epithelial cells differ from most other cell ty...

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Detalles Bibliográficos
Autores principales: Tamhankar, Manasi, Gerhardt, Dawn M., Bennett, Richard S., Murphy, Nicole, Jahrling, Peter B., Patterson, Jean L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117897/
https://www.ncbi.nlm.nih.gov/pubmed/30165875
http://dx.doi.org/10.1186/s12985-018-1045-0