Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is characterized by intracellular alpha-synuclein (α-syn) inclusions, progressive death of dopaminergic neurons in the substantia nigra pars compacta (SNpc), and activation of the innate and adaptive immune systems. Disruption of immune signaling between the cent...

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Detalles Bibliográficos
Autores principales: Williams, Gregory P., Schonhoff, Aubrey M., Jurkuvenaite, Asta, Thome, Aaron D., Standaert, David G., Harms, Ashley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117927/
https://www.ncbi.nlm.nih.gov/pubmed/30165873
http://dx.doi.org/10.1186/s12974-018-1286-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117927/
https://www.ncbi.nlm.nih.gov/pubmed/30165873
http://dx.doi.org/10.1186/s12974-018-1286-2

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