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Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors

Cancer cells have altered cellular metabolism. Mutations in genes associated with key metabolic pathways (e.g., isocitrate dehydrogenase 1 and 2, IDH1/IDH2) are important drivers of cancer, including central nervous system (CNS) tumors. Therefore, we hypothesized that the abnormal metabolic state of...

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Detalles Bibliográficos
Autores principales: Ballester, Leomar Y., Lu, Guangrong, Zorofchian, Soheil, Vantaku, Venkatrao, Putluri, Vasanta, Yan, Yuanqing, Arevalo, Octavio, Zhu, Ping, Riascos, Roy F., Sreekumar, Arun, Esquenazi, Yoshua, Putluri, Nagireddy, Zhu, Jay-Jiguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117959/
https://www.ncbi.nlm.nih.gov/pubmed/30170631
http://dx.doi.org/10.1186/s40478-018-0588-z