Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion

BACKGROUND: The long noncoding RNA Xist is critical for initiation and establishment of X-chromosome inactivation during embryogenesis in mammals, but it is unclear whether its continued expression is required for maintaining X-inactivation in vivo. RESULTS: By using an inactive X-chromosome-linked...

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Detalles Bibliográficos
Autores principales: Adrianse, Robin L., Smith, Kaleb, Gatbonton-Schwager, Tonibelle, Sripathy, Smitha P., Lao, Uyen, Foss, Eric J., Boers, Ruben G., Boers, Joachim B., Gribnau, Joost, Bedalov, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118007/
https://www.ncbi.nlm.nih.gov/pubmed/30170615
http://dx.doi.org/10.1186/s13072-018-0219-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118007/
https://www.ncbi.nlm.nih.gov/pubmed/30170615
http://dx.doi.org/10.1186/s13072-018-0219-8

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