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Perturbed maintenance of transcriptional repression on the inactive X-chromosome in the mouse brain after Xist deletion

BACKGROUND: The long noncoding RNA Xist is critical for initiation and establishment of X-chromosome inactivation during embryogenesis in mammals, but it is unclear whether its continued expression is required for maintaining X-inactivation in vivo. RESULTS: By using an inactive X-chromosome-linked...

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Detalles Bibliográficos
Autores principales:	Adrianse, Robin L., Smith, Kaleb, Gatbonton-Schwager, Tonibelle, Sripathy, Smitha P., Lao, Uyen, Foss, Eric J., Boers, Ruben G., Boers, Joachim B., Gribnau, Joost, Bedalov, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118007/ https://www.ncbi.nlm.nih.gov/pubmed/30170615 http://dx.doi.org/10.1186/s13072-018-0219-8

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