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S961, a biosynthetic insulin receptor antagonist, downregulates insulin receptor expression & suppresses the growth of breast cancer cells

BACKGROUND & OBJECTIVES: Insulin resistance associated with hyperinsulinaemia and overexpression of insulin receptors (IRs) have been intricately linked to the pathogenesis and treatment outcomes of the breast carcinoma. Studies have revealed that upregulated expression of IRs in breast cancer p...

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Detalles Bibliográficos
Autores principales: Sharma, Prateek, Kumar, Sanjeev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118145/
https://www.ncbi.nlm.nih.gov/pubmed/30168485
http://dx.doi.org/10.4103/ijmr.IJMR_403_17