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The IRF5 rs2004640 (G/T) polymorphism is not a genetic risk factor for systemic lupus erythematosus in population from south India

BACKGROUND & OBJECTIVES: Genetic aberrations disrupting toll-like receptor and interferon homeostasis enhance the risk of systemic lupus erythematosus (SLE). Raised serum interferon-alpha (IFN-α) levels in SLE patients have been ascribed to polymorphism (rs2004640 G/T) in interferon regulatory f...

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Detalles Bibliográficos
Autores principales: Devaraju, Panneer, Mehra, Sonal, Gulati, Reena, Antony, Paul T., Jain, Vikramraj K., Misra, Durga Prasanna, Negi, Vir Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118151/
https://www.ncbi.nlm.nih.gov/pubmed/30168487
http://dx.doi.org/10.4103/ijmr.IJMR_2025_16