Cargando…
Construction of an overexpression library for Mycobacterium tuberculosis
There is a pressing need to develop novel anti-tubercular drugs. High-throughput phenotypic screening yields chemical series that inhibit bacterial growth. Target identification for such series is challenging, but necessary for optimization of target engagement and the development of series into cli...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118195/ https://www.ncbi.nlm.nih.gov/pubmed/30197930 http://dx.doi.org/10.1093/biomethods/bpy009 |