Trichostatin A promotes GLI1 degradation and P21 expression in multiple myeloma cells

BACKGROUND: Histone deacetylase inhibitors are promising drugs for the future application in cancer therapy. Trichostatin A (TSA), a histone deacetylase inhibitor, exhibits effective antitumor effects in various cancers. However, the effects and underlying mechanisms of TSA on multiple myeloma (MM)...

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Detalles Bibliográficos
Autores principales: Geng, Yan, Liu, Jing, Xie, Ying, Jiang, Hongmei, Zuo, Kai, Li, Tao, Liu, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118243/
https://www.ncbi.nlm.nih.gov/pubmed/30214285
http://dx.doi.org/10.2147/CMAR.S167330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118243/
https://www.ncbi.nlm.nih.gov/pubmed/30214285
http://dx.doi.org/10.2147/CMAR.S167330

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