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Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data

Alternative splicing leverages genomic content by allowing the synthesis of multiple transcripts and, by implication, protein isoforms, from a single gene. However, estimating the abundance of transcripts produced in a given tissue from short sequencing reads is difficult and can result in both the...

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Detalles Bibliográficos
Autores principales: Newman, Jeremy R. B., Concannon, Patrick, Tardaguila, Manuel, Conesa, Ana, McIntyre, Lauren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118309/
https://www.ncbi.nlm.nih.gov/pubmed/30021829
http://dx.doi.org/10.1534/g3.118.200373