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Event Analysis: Using Transcript Events To Improve Estimates of Abundance in RNA-seq Data
Alternative splicing leverages genomic content by allowing the synthesis of multiple transcripts and, by implication, protein isoforms, from a single gene. However, estimating the abundance of transcripts produced in a given tissue from short sequencing reads is difficult and can result in both the...
Autores principales: | Newman, Jeremy R. B., Concannon, Patrick, Tardaguila, Manuel, Conesa, Ana, McIntyre, Lauren M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118309/ https://www.ncbi.nlm.nih.gov/pubmed/30021829 http://dx.doi.org/10.1534/g3.118.200373 |
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