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Acute Effects of Drugs on Caenorhabditis elegans Movement Reveal Complex Responses and Plasticity

Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal. What are the acute effects of drug treatment and how does an animal respond to these? We developed a simple assay to measure the acute effects of drugs on C. elegans movement and examined the effect...

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Detalles Bibliográficos
Autores principales: Spensley, Mark, Del Borrello, Samantha, Pajkic, Djina, Fraser, Andrew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118317/
https://www.ncbi.nlm.nih.gov/pubmed/30061375
http://dx.doi.org/10.1534/g3.118.200374