Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling

Bile acids are critical biological detergents in the gastrointestinal tract and also act as messengers to regulate a multitude of intracellular signaling events, including mitogenic signaling, lipid metabolism and endo/exocytosis. In particular, bile acids stimulate many receptors and ion channels o...

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Detalles Bibliográficos
Autores principales: Liang, Hong, Estes, Mary K., Zhang, Huiling, Du, Guangwei, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118352/
https://www.ncbi.nlm.nih.gov/pubmed/30169511
http://dx.doi.org/10.1371/journal.pone.0198983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118352/
https://www.ncbi.nlm.nih.gov/pubmed/30169511
http://dx.doi.org/10.1371/journal.pone.0198983

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