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Feasibility of developing reliable gene expression modules from FFPE derived RNA profiled on Affymetrix arrays

The reliability of differential gene expression analysis on formalin-fixed, paraffin-embedded (FFPE) expression profiles generated using Affymetrix arrays is questionable, due to the high range of percent-present values reported in studies which profiled FFPE samples using this technology. Moreover,...

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Detalles Bibliográficos
Autores principales: Jose, Vinu, Fumagalli, Debora, Rothé, Françoise, Majjaj, Samira, Loi, Sherene, Michiels, Stefan, Sotiriou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118369/
https://www.ncbi.nlm.nih.gov/pubmed/30169535
http://dx.doi.org/10.1371/journal.pone.0203346