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Ablation of Ezh2 in neural crest cells leads to aberrant enteric nervous system development in mice

In the current study, we examined the role of Ezh2 as an epigenetic modifier for the enteric neural crest cell development through H3K27me3. Ezh2 conditional null mice were viable up to birth, but died within the first hour of life. In addition to craniofacial defects, Ezh2 conditional null mice dis...

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Detalles Bibliográficos
Autores principales: Kim, Hana, Langohr, Ingeborg M., Faisal, Mohammad, McNulty, Margaret, Thorn, Caitlin, Kim, Joomyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118393/
https://www.ncbi.nlm.nih.gov/pubmed/30169530
http://dx.doi.org/10.1371/journal.pone.0203391