Encoding canonical DNA quadruplex structure

The main challenge in DNA quadruplex design is to encode a three-dimensional structure into the primary sequence, despite its multiple, repetitive guanine segments. We identify and detail structural elements describing all 14 feasible canonical quadruplex scaffolds and demonstrate their use in contr...

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Detalles Bibliográficos
Autores principales: Dvorkin, Scarlett A., Karsisiotis, Andreas I., Webba da Silva, Mateus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118410/
https://www.ncbi.nlm.nih.gov/pubmed/30182059
http://dx.doi.org/10.1126/sciadv.aat3007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118410/
https://www.ncbi.nlm.nih.gov/pubmed/30182059
http://dx.doi.org/10.1126/sciadv.aat3007

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