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Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors

Control of cellular metabolism is critical for efficient cell function, although little is known about the interplay between cell subset–specific metabolites in situ, especially in the tumor setting. Here, we determined how a macrophage-specific (Mϕ-specific) metabolite, itaconic acid, can regulate...

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Detalles Bibliográficos
Autores principales: Weiss, Jonathan M., Davies, Luke C., Karwan, Megan, Ileva, Lilia, Ozaki, Michelle K., Cheng, Robert Y.S., Ridnour, Lisa A., Annunziata, Christina M., Wink, David A., McVicar, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118601/
https://www.ncbi.nlm.nih.gov/pubmed/29920191
http://dx.doi.org/10.1172/JCI99169